Samson starts with 3 red heart containers and Bloody Lust. Samson is unlocked when the player defeats two floors in a row without taking any damage. Eve will start with the Razor Blade regardless of whether it is unlocked or not as long as 439 coins have been donated to the Greed Machine. However, if the Razor Blade has not been unlocked by defeating Satan with Eve, Eve will not start with the Razor Blade until both conditions have been fulfilled. Eve starts with two red heart containers, Whore of Babylon, and the Dead Bird.Įve will also start with the Razor Blade upon donating 439 coins to the Greed Machine.

If an item would grant him a red heart container (including an empty one), it adds a soul heart instead.Įve is a character unlocked by beating two floors in a row without collecting any heart pickups. He starts with three soul hearts, and his health meter is unique in that he cannot gain red heart containers. ?, also known as the Blue Baby, is a character unlocked by defeating Mom's Heart ten times.

Judas starts with one red heart container but has The Book of Belial upon starting, as well as 3 coins. Judas is a character unlocked after beating Satan for the first time. He starts with two red heart containers, the Lucky Foot, and one key.Ĭain will also start with the Paper Clip trinket if 68 coins have been donated to the Greed Machine. If the Aprils Fool challenge is completed, she will also start with a Speed Up pill.Ĭain is unlocked when the player owns 55 or more coins at once in a run. Magdalene starts with four red heart containers and the Yum Heart. Magdalene, or Maggy, is unlocked when the player obtains seven or more heart containers at once in a run.

Black hearts binding of isaac